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New hope for diabetes patients
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11 January 2008
A pooled data study involving almost 90,000 participants found that a wide range of patients benefited from the treatment, irrespective of what kind of diabetes they had.
Over an average period of 4.3 years, deaths among diabetes sufferers fell by 9% for every step reduction in "bad" cholesterol levels.
People without diabetes experienced a death rate reduction that was only slightly higher.
The number of major cardiovascular events such as heart attacks and strokes fell by a fifth for every millimole per litre reduction in blood levels of low density lipoprotein (LDL), or "bad" cholesterol.
Again the effect was similar in people with and without diabetes.
Diabetes is known to increase the risk of heart and artery disease. However although previous research has supported the its treatment with statins, the effect of the drugs on major coronary events including death has not been clear.
It was also uncertain whether statins were as effective for diabetic patients as for those without the disease.
Researchers from the Oxford-based Cholesterol Treatment Trialists Collaboration, working with colleagues in Australia, pooled together and analysed results from 14 randomised trials. The studies included 18,686 patients with both Type 1 and Type 2 diabetes, and 71,370 without diabetes.
Writing in The Lancet medical journal, the authors concluded: "This meta-analysis shows convincingly that the proportional benefits of statin therapy on major vascular events were similar in a wide range of individuals with diabetes, including those with no previous history of vascular disease, and benefits were similar to those observed in people without diabetes."
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