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Harrington's one-over-par score at Oakland Hills left him three shots off the lead at the end of a round cut short for the day at 8.39pm because of nightfall, with 18 players still to finish.

Earlier, the round had been suspended for one hour and 25 minutes due to rain and forecasts of lightning.

Karlsson and Milka Singh were safely in the clubhouse, having made the early running with opening rounds of 68, one stroke clear of Sergio Garcia and American trio Sean O'Hair, Ken Duke and Billy Mayfair.

Argentina's Andres Romero was also two under, having played 16 holes of his first round.

Sweden's Karlsson, a top-10 finisher in each of the first three majors of 2008, bounced back from an opening double-bogey at the par-four first hole to birdie five of the next seven.

He added another at the 11th before bogeys at the par-four 14th and 15th holes sent him back to two under for his round.

Among those yet to complete their opening rounds were South Africa's Retief Goosen and American Jonathan Byrd, who both shared the lead at three under before bogeying the eighth and 17th holes respectively.

Anthony Kim, a two-time PGA Tour winner in his second season, and world number two Phil Mickelson both carded level-par 70s.