Brett Favre savoured a triumphant but frosty homecoming, throwing four touchdowns as the Minnesota Vikings beat the Green Bay Packers 38-26 in the NFL.

If walking out to waves of loud jeers from his former fans threw Favre off his game, it didn't last long. Despite being jeered repeatedly by Packers fans who once cheered his every move, Favre completed 17 of 28 passes for 244 yards and four touchdowns.

The Vikings, with seven wins and a loss, took a firm hold on the NFC North standings.

Rookie receiver Percy Harvin caught five passes for 84 yards and a touchdown and had five returns for 175 yards.

The Vikings' defense roughed up Favre's successor, Aaron Rodgers, sacking him six times. But with the Packers (4-3) on the verge of getting routed, Rodgers rebounded with three second-half touchdowns.

Favre left the field surrounded by cameras, pumping his fist to a mix of cheers and boos as he jogged down the tunnel.

Despite the final score, it was an awkward homecoming for Favre, whose high-profile standoff with the front office split the loyalties of Packers fans last summer. Rams 17, Lions 10
At Detroit, Steven Jackson's 25-yard touchdown run with 1:38 left ended St. Louis' 17-game losing streak, helping the Rams avoid match their worst start in the club's history.

They also ended talk about joining Detroit, which has one win this season, as the only teams in NFL history to have an 0-16 season.

St. Louis hadn't won since beating Dallas on Oct. 19, 2008. Colts 18, 49ers 14.

At Indianapolis, the Colts won their 16th straight regular-season game and Jim Caldwell became the first rookie coach since the NFL merger to open his career with seven consecutive wins.

Peyton Manning topped 300 yards and got credit for another Colts rally, but it was Joseph Addai who won it. The fourth-year running back threw a 22-yard touchdown pass to Reggie Wayne early in the final quarter to give the Colts their only lead.

The Colts are the last unbeaten team in the AFC for the fourth time in five years. Ravens 30, Broncos 7.

At Baltimore, the Ravens handed Denver its first loss of the season.

Rookie Lardarius Webb returned the second-half kickoff 95 yards for a touchdown, and the Ravens ended a three-game losing streak with a surprisingly easy victory.

It was Denver's first loss under rookie head coach Josh McDaniels. Titans 30, Jaguars 13
At Nashville, Vince Young threw for a touchdown in his first start since the 2008 season opener and Chris Johnson set a franchise record by rushing for 228 yards as the Titans won their first game of the season. Tampa Bay, which had a bye this week, remains the only winless team. Chargers 24, Raiders 16.

At San Diego, LaDainian Tomlinson scored twice as the Chargers took their 13th straight victory against the Raiders. It's the longest active NFL winning streak by one team over another. Panthers 34, Cardinals 21.

At Glendale, Arizona, Jake Delhomme threw a 50-yard touchdown pass before leaving with a chest injury and Jonathan Stewart ran for two scores.

The Panthers, in a turnover-free performance, rolled up 270 yards on the ground against what had been the No. 1 rushing defense in the NFL. Eagles 40, Giants 17.

At Philadelphia, Donovan McNabb threw three touchdown passes and DeSean Jackson had another big TD catch for the Eagles. The game was just the appetizer in a marathon day in the NY-Philadelphia rivalry. The Yankees and Phillies were set for the first pitch of Game 4 of the World Series across the street only hours after the Eagles' rout ended. Cowboys 38, Seahawks 17
At Arlington, Texas, Miles Austin caught a touchdown pass for the third straight game and Patrick Crayton returned a punt for a score for the second consecutive week, sending Dallas into a share of first place in the NFC East.

Tony Romo went a third game in a row without an interception. Since a herky-jerky first month, the Cowboys (5-2) have found quite a groove, winning three straight. Dolphins 30, Jets 25
At East Rutherford, Ted Ginn Jr. had two long kickoff returns for touchdowns in the third quarter. Texans 31, Bills 10.

At Orchard Park, New York, Ryan Moats scored three touchdowns on consecutive fourth-quarter drives to help the Texans win their third straight game. Bears 30, Browns 6.

At Chicago, Jay Cutler threw for 225 yards and Matt Forte ran for two touchdowns as the Bears beat the bumbling Browns.

The Bears paid tribute to Walter Payton at halftime on the 10th anniversary of his death, then delivered a performance that was far from sweet. But it was effective enough.